The National Institute of Mental Health (NIMH) has
embarked on yet another clinical trial to evaluate women with depression
perimenopause. Depression perimenopause, which may manifest itself with
anxiety, anger and mood swings along with text-book depression, is not a
perimenopause symptom in itself. Recent studies conclude that
perimenopause does not cause depression, but that the hormone
fluctuation in perimenopause act as a trigger for pre-existing
depression, anger, anxiety and mood swing issues.
While perimenopause is a period of increased risk
for depression, a history of depression also places women at an
increased risk for an earlier onset of depression perimenopause.
The purpose of the depression perimenopause study is to investigate mood
and behavior changes in the time period surrounding and including
menopause. This is an observational study; volunteers who participate
will not receive any new or experimental therapies.
Controversy exists regarding the relationship between estrogen and
progesterone (gonadal steroid) changes and midlife-onset depression. The
depression perimenopause study will examine the role of gonadal steroids
in perimenopausal mood and behavioral disorders.
Perimenopausal women with depression symptoms and a control group of
healthy perimenopausal volunteers will be compared to identify
correlates of the occurrence of depression perimenopause. Participants
with depressive symptoms may also participate in companion studies that
will test the antidepressant efficacy of phytoestrogens and selective
estrogen receptor modulators (SERMS).
A group of younger pre-perimenopausal women with normal menstrual cycle
functioning will be followed through menopause in an effort to confirm
the association of depression onset with changes in reproductive
endocrine functioning. Approximately 600 women are anticipated to take
part in this depression perimenopause study.
More about the study to follow, but keep in mind that this is only an
observational study and that findings are years away. If you are
suffering from depression perimenopause, current safe, effective relief
is needed. Visit our new depression section for valuable information on
our new extremely efficacious product.
Following is the inclusion criteria for the depression perimenopause
study:
- Female.
- History within the last one year of at
least one month with perimenopause or midlife-related mood or
behavioral disturbances of at least moderate severity - that is,
disturbances that are distinct in appearance and associated with a
notable degree of functional impairmen.
- Age 40-60.
- History of the onset of menstrual irregularity
during the past six months but not greater than one year of amenorrhea
(i.e., not postmenopausal).
- Biological evidence of a deterioration of
normal ovarian activity, specifically, plasma FSH levels persistently
elevated (greater than 14 IU/L) drawn at two week intervals over a
period of eight weeks.
- No prior estrogen replacement therapy for
treatment of perimenopausal physical or emotional symptoms within the
last six months.
- Good medical health.
A control group of age-matched perimenopausal
women who meet patient selection criteria with the exception of the
presence of mood or behavioral disorders will also be sought.
LONGITUDINAL SCREENING:
The pre-perimenopausal women (regular cycling) will be women who meet
the following criteria:
- Female.
- Regular menstrual cycle function (21-34 days).
- Absence of current mood or behavioral
disturbances as determined by a structured diagnostic interview,.
- Early follicular phase plasma gonadotropin
levels in pre-perimenopausal range (less than 14 IU/L).
- In good medical health,.
- Medication free.
Special Instructions:
Call referral contact for additional eligibility criteria. Refer to:
Title: A Screening Protocol to Evaluate Women with Perimenopause-Related
Mood and Behavioral Disorders
Number: 88-M-0131
|
 |
Diosgenin cream ingredients
| Benefits diosgenin cream |
How to use diosgenin cream. |
Return to Eden Diosgenin (nicknamed Progesterone) Cream.
Sorry - Product Discontinued
NEW!! NEW!!! BIG DRUG COMPANIES
USING THE FEDERAL TRADE COMMISSION IN AN ATTEMPT TO DESTROY COMPETITION FROM
NATURAL HORMONE REPLACEMENT THERAPIES!!!
Do you remember our newsletter
last year detailing how Wyeth Pharmaceuticals was attempting to stop
compounding pharmacists from prescribing natural progesterone (diosgenin)
after their profits fell by more than 57% from $2.07 billion in 2003 to
$800 million in 2004 (after the WHI study had to be stopped)?
Well, now they have gone after
centers like ours making complaints to the Federal Trade Commission
(FTC). The FTC's position backed by the big pharmaceutical companies is
that Dr. John Lee, M.D.'s studies were not scientific and did not rise to
the standard of FDA and National Institutes of Health studies, and that
our claims about natural progesterone are false, unfair, deceptive,
misleading advertising in violation of the law..
(Please read
what Dr. Helen Pensanti M.D. has to say about this. Read on to how the study
was conducted.)
This is an attempt to force women into taking
unsafe proven cancer causing synthetic hormones using
your tax dollar to harass natural hormone suppliers. We here at the Women's
Menopause Health Center refuse to take away your choice of a healthy
alternative to Premarin, Prempro and the other dangerous drugs. We are
taking a stand against this heavy handed attempt to destroy competition. We
are going to fight for your choice of a healthy way to get through menopause
comfortably and safely.
(Ed. note: This was from our newsletter last year. The
continued harassment by the FTC has caused us to discontinue our wonderful
product. DO NOT be forced
into taking something that can kill you. You may purchase safe
progesterone cream at your local health food store, or find it a lot less
expensively on line at places like ebay and yahoo stores.
Do not let these heavy handed tactics destroy your health!)
Return to Eden Chemical
Preservative FREE
Natural Progesterone Cream.
-
ALL NATURAL INGREDIENTS -
ARTIFICIAL AND CHEMICAL PRESERVATIVE FREE!
-
HIGHEST QUALITY NATURAL
INGREDIENTS USP PROGESTERONE CREAM ON MARKET TODAY.
-
500 MG/OZ USP PROGESTERONE, 100% PHARMACEUTICAL GRADE.
1-
4oz jar
Return to Eden Progesterone Cream
MSRP $26.99 $19.95
2- 4oz jars
Return to Eden Progesterone Cream
$35.95 |
Contacts:
Linda Simpson-St. Clair, R.N.
National Institutes of Health
Building 10
Room 3N238
10 Center Drive
Bethesda, Maryland 20892
Phone: (301) 496-9576
Fax: (301) 402-2588
Electronic Address: simpsonl@irp.nimh.nih.gov
Menopause
Recipes: Anne's Healthier Whipped Butter.
TLC Bath & Body Recipe:
Rose Petal Bath.
Exercise Tip: Nordic
Walking.
Return to the Archived Newsletter
Index.
